Sodium hydride → HCID 54150617, compound

HRID 1702893Notes

Reaction equation

HRID 1702893 reaction equation
[H-].[Na+].[C:3]1([C:9]2[NH:10][C:11](=[O:21])[N:12]([CH3:20])[C:13]=2[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH3:22][O:23][C:24](=[O:33])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31]Br>CN(C=O)C>[CH3:22][O:23][C:24](=[O:33])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][N:10]1[C:9]([C:3]2[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=2)=[C:13]([C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)[N:12]([CH3:20])[C:11]1=[O:21]

Participants

5

Reactant 3

HCID 24758Sodium hydrideHCID 11107373Methyl 8-bromooctanoateHCID 113910531,3-Dihydro-1-methyl-4,5-diphenyl-2H-imidazol-2-one

Product 1

HCID 54150617HCID 54150617, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The product is produced as described in example 1 from 2.4 g of NaH (80% suspension in mineral oil), 20 g of 4.5-diphenyl-1-methyl-4-imidazolin-2-one, 160 cc. of DMF, 19 g of 8-bromocaprylic acid methyl ester and 2.4 g of NaJ.

Workup

  1. customThe product is produced

Sources & evidence

ORD record
ord-a9853a1ce8f14940a0684546e63e0b95
Source dataset
uspto-grants-1982_09
Patent number
US04349684

Reaction notes

Loading…