Tetrahydrofuran → HCID 22761659, compound

HRID 1703469Notes

Reaction equation

HRID 1703469 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[C:14](=[O:15])[C:13]3=[CH:16][C:17]([Cl:20])=[CH:18][CH:19]=[C:12]3[C:11]2=[O:21])=[C:6]([CH2:22]I)[CH:5]=1)([O-:3])=[O:2].[O:24]1CCC[CH2:25]1>CO.C(=O)([O-])[O-].[Ag+2]>[CH3:25][O:24][CH2:22][C:6]1[CH:5]=[C:4]([N+:1]([O-:3])=[O:2])[CH:9]=[CH:8][C:7]=1[N:10]1[C:14](=[O:15])[C:13]2=[CH:16][C:17]([Cl:20])=[CH:18][CH:19]=[C:12]2[C:11]1=[O:21]

Participants

5

Reactant 2

HCID 8028TetrahydrofuranHCID 22761648HCID 22761648, compound

Product 1

HCID 22761659HCID 22761659, compound

Reagents, catalysts & solvents 2

HCID 178418647HCID 178418647, compoundCatalystHCID 887MethanolSolvent

Procedure

The starting material is prepared as follows: The solution of 2 g of N-(4-nitro-2-iodomethylphenyl)-4-chlorophthalimide in 40 ml of tetrahydrofuran and 40 ml of methanol, is treated with 8.7 g of freshly prepared silver carbonate for 20 hours, with protection from light. The mixture is filtered and the filtrate evaporated, to yield the N-(2-methoxymethyl-4-nitrophenyl)-4-chlorophthalimide melting at 125°-128°.

Workup

  1. customThe starting material is prepared
  2. filtrationThe mixture is filtered
  3. customthe filtrate evaporated

Sources & evidence

ORD record
ord-3b8b86c1a3d445d98532f62a98595bd5
Source dataset
uspto-grants-1978_11
Patent number
US04124593

Reaction notes

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