Hydrogen Bromide → HCID 86736144, compound

HRID 1703772Notes

Reaction equation

HRID 1703772 reaction equation
[I:1][C:2]1[CH:10]=[CH:9][C:5]([CH2:6][CH2:7]O)=[CH:4][CH:3]=1.Br.NC(N)=[S:14]>O>[I:1][C:2]1[CH:10]=[CH:9][C:5]([CH2:6][CH2:7][SH:14])=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 260Hydrogen BromideHCID 2723790ThioureaHCID 30407702-(4-Iodophenyl)ethan-1-ol

Product 1

HCID 86736144HCID 86736144, compoundYield 27%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

104 g of p-iodophenethyl alcohol was combined in solution with 216 g of hydrobromic acid (48%) and 36 g of thiourea in 100 ml of water and reacted in accordance with the procedure outlined in Example I(a). Vacuum distillation at 91°-95° and 0.2 mm Hg gave a 27% yield of p-iodophenethyl thiol having a refractive index of n25D = 1.6411, an ALD of 0.56 ml/Kg and a formula of C8H8IS.

Workup

  1. customreacted in accordance with the procedure
  2. distillationVacuum distillation at 91°-95°

Sources & evidence

ORD record
ord-e53dbd045c9745fea033e8bf86d74c4d
Source dataset
uspto-grants-1978_11
Patent number
US04125554

Reaction notes

Loading…