N,N'-Diethylthiourea → HCID 70618079, compound

HRID 1703898Notes

Reaction equation

HRID 1703898 reaction equation
[Cl:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([S:12](=[O:16])(=[O:15])[NH:13][CH3:14])[CH:6]=1)=[O:4].[CH2:17]([NH:19][C:20]([NH:22][CH2:23][CH3:24])=[S:21])[CH3:18]>C(OC(C)C)(C)C>[ClH:1].[CH2:23]([N:22]1[C:3]([C:5]2[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([S:12](=[O:16])(=[O:15])[NH:13][CH3:14])[CH:6]=2)([OH:4])[CH2:2][S:21][C:20]1=[N:19][CH2:17][CH3:18])[CH3:24]

Participants

4

Reactant 2

HCID 2735009N,N'-DiethylthioureaHCID 20476829HCID 20476829, compound

Product 1

HCID 70618079HCID 70618079, compound

Reagents, catalysts & solvents 1

HCID 7914Diisopropyl EtherSolvent

Procedure

5.6 g of 2,4'-dichloro-3'-methylsulfamoylacetophenone and 2.7 g of 1,3-diethylthiourea were reacted as prescribed in Example 12. After the addition of 100 ml of diisopropyl ether and a dwelling period of 1 hour at 0° C., the solvent was decanted and the oily end product was crystallized under boiling diethyl ether. Colorless solid body, melting point: 168° C. (decomposition).

Workup

  1. customa dwelling period of 1 hour at 0° C., the solvent was decanted
  2. customthe oily end product was crystallized under boiling diethyl ether

Sources & evidence

ORD record
ord-dc69e1e785844803a3f32b86a7dc766e
Source dataset
uspto-grants-1978_11
Patent number
US04125614

Reaction notes

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