N,N'-Diethylthiourea → HCID 22760486, compound

HRID 1703900Notes

Reaction equation

HRID 1703900 reaction equation
[CH2:1]([NH:5][S:6]([C:9]1[CH:10]=[C:11]([C:16](=[O:19])[CH2:17]Cl)[CH:12]=[CH:13][C:14]=1[Cl:15])(=[O:8])=[O:7])[CH2:2][CH2:3][CH3:4].[CH2:20]([NH:22][C:23]([NH:25][CH2:26][CH3:27])=[S:24])[CH3:21]>C(OC(C)C)(C)C>[ClH:15].[CH2:26]([N:25]1[C:16]([C:11]2[CH:12]=[CH:13][C:14]([Cl:15])=[C:9]([S:6](=[O:8])(=[O:7])[NH:5][CH2:1][CH2:2][CH2:3][CH3:4])[CH:10]=2)([OH:19])[CH2:17][S:24][C:23]1=[N:22][CH2:20][CH3:21])[CH3:27]

Participants

4

Reactant 2

HCID 2735009N,N'-DiethylthioureaHCID 54206016HCID 54206016, compound

Product 1

HCID 22760486HCID 22760486, compound

Reagents, catalysts & solvents 1

HCID 7914Diisopropyl EtherSolvent

Procedure

6.4 g of 3'-n-butylsulfamoyl-2,4'-dichloroacetophenone and 2.7 g of ground 1,3-diethylthiourea were reacted as prescribed in Example 12. With the addition of 200 ml of diisopropyl ether, the oily end product was precipitated and the solvent was decanted. The amorphous residue was dissolved in 100 ml of water and liophylized. Colorless solid body, decomposition beginning at 130° C., γ C=N 1620 cm-1.

Workup

  1. customthe oily end product was precipitated
  2. customthe solvent was decanted
  3. dissolutionThe amorphous residue was dissolved in 100 ml of water
  4. customat 130° C.

Sources & evidence

ORD record
ord-c20e4c079d4e431786656bb9f8742075
Source dataset
uspto-grants-1978_11
Patent number
US04125614

Reaction notes

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