Tetrahydrofuran → 4'-[(1-{[5-({[Tert-butyl(dimethyl)silyl]oxy}methyl)pyridin-2-yl]methyl}-2-methyl-6-oxo-4-propyl-1,6-dihydropyrimidin-5-yl)methyl]biphenyl-2-carbonitrile
Reaction equation
[C:58]([CH3:59])([CH3:60])([CH3:61])[Si:62]([O:63][CH2:64][c:65]1[cH:66][cH:67][c:68]([CH2:71][OH:72])[n:69][cH:70]1)([CH3:73])[CH3:74].[CH2:45]([P:46]([CH2:47][CH2:48][CH2:49][CH3:50])[CH2:51][CH2:52][CH2:53][CH3:54])[CH2:55][CH2:56][CH3:57].[CH3:1][c:2]1[nH:3][c:4](=[O:26])[c:5]([CH2:11][c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19]([C:24]#[N:25])[cH:20][cH:21][cH:22][cH:23]3)[cH:16][cH:17]2)[c:6]([CH2:8][CH2:9][CH3:10])[n:7]1.[N:27]([C:28]([N:29]1[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]1)=[O:35])=[N:36][C:37]([N:38]1[CH2:39][CH2:40][CH2:41][CH2:42][CH2:43]1)=[O:44].[O:75]1[CH2:76][CH2:77][CH2:78][CH2:79]1>>[CH3:1][c:2]1[n:3]([CH2:71][c:68]2[cH:67][cH:66][c:65]([CH2:64][O:63][Si:62]([C:58]([CH3:59])([CH3:60])[CH3:61])([CH3:73])[CH3:74])[cH:70][n:69]2)[c:4](=[O:26])[c:5]([CH2:11][c:12]2[cH:13][cH:14][c:15](-[c:18]3[c:19]([C:24]#[N:25])[cH:20][cH:21][cH:22][cH:23]3)[cH:16][cH:17]2)[c:6]([CH2:8][CH2:9][CH3:10])[n:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-47052ee6d2fe4429a801dd67be8a2f9f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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