HRID1704841

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7805

4-Bromotoluene

C7H7Br

HCID7961

Bromobenzene

C6H5Br

结构：Cc1cc2n(-c3ccccc3)c(=O)c3cnc4[nH]ncc4c3n2n1

HCID22757453

未命名化合物

结构：Cc1cc2n(-c3ccccc3)c(=O)c3cnc4c(cnn4C(=O)c4ccccc4)c3n2n1

HCID22757466

未命名化合物

结构：CC1C=C2N(c3ccccc3)C(=O)c3cnc4[nH]ncc4c3N2N1Cc1ccco1

HCID22757469

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(-n2c(=O)c3cnc4c(cnn4C(=O)c4ccccc4)c3n3nc(C)cc23)cc1

HCID22757500

未命名化合物

PROCEDURE

实验过程

By substituting p-methylphenyl bromide for the bromobenzene in the procedure of Example 21 (a), and proceeding as in parts (b) and (c), 8-benzoyl-2-methyl-4-(p-methylphenyl)-4H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[3,4-e]pyrimidin-5(8H)-one is obtained.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f47e46a5a51b4f2cba46045a569cf6cc
来源数据集: uspto-grants-1978_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04127657
来源说明: uspto-grants-1978_11

反应 SMILES

[CH3:1]C1C=CC(Br)=CC=1.BrC1C=CC=CC=1.C(N1N2C3C4C=NNC=4N=CC=3C(=O)N(C3C=CC=CC=3)C2=CC1C)C1OC=CC=1.CC1C=C2N(C3C=CC=CC=3)C(=O)C3C=NC4NN=CC=4C=3N2N=1.[C:70]([N:78]1[C:82]2[N:83]=[CH:84][C:85]3[C:86](=[O:101])[N:87]([C:95]4[CH:100]=[CH:99][CH:98]=[CH:97][CH:96]=4)[C:88]4[N:89]([N:91]=[C:92]([CH3:94])[CH:93]=4)[C:90]=3[C:81]=2[CH:80]=[N:79]1)(=[O:77])[C:71]1[CH:76]=[CH:75][CH:74]=[CH:73][CH:72]=1>>[C:70]([N:78]1[C:82]2[N:83]=[CH:84][C:85]3[C:86](=[O:101])[N:87]([C:95]4[CH:100]=[CH:99][C:98]([CH3:1])=[CH:97][CH:96]=4)[C:88]4[N:89]([N:91]=[C:92]([CH3:94])[CH:93]=4)[C:90]=3[C:81]=2[CH:80]=[N:79]1)(=[O:77])[C:71]1[CH:76]=[CH:75][CH:74]=[CH:73][CH:72]=1