Dichloromethane → 2-Isopropyl-3-hydroxymethyl-4-(4-fluorophenyl)-5,6,7,8-tetrahydro-8,8-dimethylquinoline
Reaction equation
[Al+3:29].[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42].[CH:1]([CH3:2])([CH3:3])[c:4]1[n:5][c:6]2[c:11]([c:12](-[c:19]3[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]3)[c:13]1[C:14](=[O:15])[O:16][CH2:17][CH3:18])[CH2:10][CH2:9][CH2:8][C:7]2([CH3:26])[CH3:27].[Cl:34][CH2:35][Cl:36].[H-:28].[H-:31].[H-:32].[H-:33].[Li+:30]>>[CH:1]([CH3:2])([CH3:3])[c:4]1[n:5][c:6]2[c:11]([c:12](-[c:19]3[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]3)[c:13]1[CH2:14][OH:15])[CH2:10][CH2:9][CH2:8][C:7]2([CH3:26])[CH3:27]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-3dbd0cb0890f487fb583ee1b92d810ef
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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