Triphenylphosphine → (2,5-Dimethoxybenzyl)(triphenyl)phosphonium bromide

HRID 1706262Notes

Reaction equation

HRID 1706262 reaction equation
[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][C:4]=1[CH2:5][Br:6].[C:13]1([P:19]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C(#N)C>[Br-:6].[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][C:4]=1[CH2:5][P+:19]([C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 5920212-(Bromomethyl)-1,4-dimethoxybenzene

Product 1

HCID 19605777(2,5-Dimethoxybenzyl)(triphenyl)phosphonium bromide

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The 2,5-dimethoxybenzyl triphenylphosphonium bromide is prepared by refluxing a mixture of 2,5-dimethoxybenzyl bromide (12 g.) and triphenylphosphine (14.2.) in acetonitrile (200 ml.) for one hour and isolating the product by standard methods.

Workup

  1. temperatureby refluxing
  2. customisolating the product by standard methods

Sources & evidence

ORD record
ord-25c7103be80d4232a5667bfba9256227
Source dataset
uspto-grants-1980_06
Patent number
US04206225

Reaction notes

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