6-Hydrazinylpyridine-3-sulfonamide → HCID 136210765, compound

HRID 1706307Notes

Reaction equation

HRID 1706307 reaction equation
[C:1]([CH:4]([O:6][C:7]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[C:10](=[O:17])[C:9](=O)[CH:8]=1)[CH3:5])([OH:3])=[O:2].[NH:19]([C:21]1[CH:26]=[CH:25][C:24]([S:27](=[O:30])(=[O:29])[NH2:28])=[CH:23][N:22]=1)[NH2:20]>Cl.C(O)(=O)C>[S:27]([C:24]1[CH:25]=[CH:26][C:21]([N:19]=[N:20][C:9]2[CH:8]=[C:7]([O:6][CH:4]([C:1]([OH:3])=[O:2])[CH3:5])[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[C:10]=2[OH:17])=[N:22][CH:23]=1)(=[O:29])(=[O:30])[NH2:28]

Participants

5

Reactant 2

HCID 120965906-Hydrazinylpyridine-3-sulfonamideHCID 23456142HCID 23456142, compound

Product 1

HCID 136210765HCID 136210765, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidCatalystHCID 176Acetic AcidSolvent

Procedure

4-(1-Carboxyethoxy)-1,2-naphthoquinone (0.26 g, 1.06×10-3 mole) and 2-hydrazino-5-sulfamoylpyridine (0.2 g, 1.06×10-3 mole) were added to acetic acid (5 ml), along with 2 to 3 drops of concentrated hydrochloric acid. After stirring for 3 hours, at room temperature, the mixture was filtered to remove traces of solid. The filtrate was poured into distilled water (30 ml) and filtered again. The precipitate was washed with water and air dried; yield 0.26 g (59 percent).

Workup

  1. filtrationthe mixture was filtered
  2. customto remove traces of solid
  3. additionThe filtrate was poured
  4. distillationinto distilled water (30 ml)
  5. filtrationfiltered again
  6. washThe precipitate was washed with water and air
  7. customdried

Sources & evidence

ORD record
ord-5a7c194cbd1243248a1dbdc72c408cea
Source dataset
uspto-grants-1980_06
Patent number
US04207104

Reaction notes

Loading…