HCID 23456142, compound → HCID 136149070, compound

HRID 1706311Notes

Reaction equation

HRID 1706311 reaction equation
[C:1]([CH:4]([O:6][C:7]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[C:10](=[O:17])[C:9](=O)[CH:8]=1)[CH3:5])([OH:3])=[O:2].[NH:19]([C:21]1[C:26]([O:27][CH3:28])=[CH:25][C:24]([S:29](=[O:32])(=[O:31])[NH2:30])=[CH:23][N:22]=1)[NH2:20]>Cl.C(O)(=O)C>[CH3:28][O:27][C:26]1[C:21]([N:19]=[N:20][C:9]2[CH:8]=[C:7]([O:6][CH:4]([C:1]([OH:3])=[O:2])[CH3:5])[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[C:10]=2[OH:17])=[N:22][CH:23]=[C:24]([S:29](=[O:32])(=[O:31])[NH2:30])[CH:25]=1

Participants

5

Reactant 2

HCID 23456142HCID 23456142, compoundHCID 234561476-Hydrazinyl-5-methoxy-3-pyridinesulfonamide

Product 1

HCID 136149070HCID 136149070, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidCatalystHCID 176Acetic AcidSolvent

Procedure

4-(1-Carboxyethoxy)-1,2-naphthoquinone (0.22 g, 9×10-4) and 2-hydrazino-3-methoxy-5-sulfamoylpyridine (0.2 g, 9×10-4 mole) were added to acetic acid (15 ml), along with 2 to 3 drops of concentrated hydrochloric acid. After stirring overnight, the resulting precipitate was collected by filtration, air dried, slurried twice with boiling acetic acid (5 ml) and isolated again by filtration; yield, 80 mg (20 percent).

Workup

  1. filtrationthe resulting precipitate was collected by filtration, air
  2. customdried
  3. customisolated again by filtration
  4. customyield

Sources & evidence

ORD record
ord-beb787eea94a4651a7b2de578dbd4325
Source dataset
uspto-grants-1980_06
Patent number
US04207104

Reaction notes

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