Methylamine → HCID 57178653, compound

HRID 1706687Notes

Reaction equation

HRID 1706687 reaction equation
O=[C:2]1[C:7]2[N:8]=[CH:9][S:10][C:6]=2[CH2:5][CH2:4][CH2:3]1.[CH3:11][NH2:12]>C(O)C>[CH3:11][N:12]=[C:2]1[C:7]2[N:8]=[CH:9][S:10][C:6]=2[CH2:5][CH2:4][CH2:3]1

Participants

4

Reactant 2

HCID 6329MethylamineHCID 198391244(5H)-Benzothiazolone, 6,7-dihydro-

Product 1

HCID 57178653HCID 57178653, compoundYield 86%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

6 g (0.039 mole) of the ketone obtained in step (d) are dissolved in 50 ml anhydrous ethanol and treated for 30 minutes with a gaseous methylamine stream. After evaporation to dryness, the residue is taken up into ether and filtered, to give 5.6 g (86%) of product, M.p. 233°-235° C.

Workup

  1. customAfter evaporation to dryness
  2. filtrationfiltered

Sources & evidence

ORD record
ord-b61f206962e54c0791738650f81f1812
Source dataset
uspto-grants-1980_06
Patent number
US04208420

Reaction notes

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