Dimethylformamide → Glucose Monohydrate

HRID 1707031Notes

Reaction equation

HRID 1707031 reaction equation
CC1[O:7]C([O:8][CH:9]2[C:15]3[C:16]([OH:33])=C4C(=O)C5C(=CC(OC)=CC=5O)C(=O)C4=CC=3[C:12](=[O:13])[C:11]([OH:35])(C)[CH:10]2[O:36]C)C(OC)C(O)C1OC.CN(C)C=[O:46]>C(Cl)(Cl)Cl.CO>[OH2:7].[O:13]=[CH:12][C@@H:11]([C@H:10]([C@@H:9]([C@@H:15]([CH2:16][OH:33])[OH:46])[OH:8])[OH:36])[OH:35]

Participants

4

Reactant 2

HCID 6228DimethylformamideHCID 99762Steffimycin B

Product 1

HCID 22814120Glucose Monohydrate

Reagents, catalysts & solvents 1

HCID 21584188Chloroform methanolSolvent

Procedure

Between about 36 and 48 hours of fermentation time, steffimycin B is added to the fermentation as a dimethylformamide solution (25 mg/ml) to a final medium concentration of 25 mg/l. The fermentation is monitored using tlc on silica gel plates with CHCl3 :CH3OH (925:75) as the developing solvent system. The tlc procedure is conducted at half day intervals between the first half day and five days.

Workup

  1. custombetween the first half day and five days

Sources & evidence

ORD record
ord-ceefcb6dbfae4936bb6c858e19268d8f
Source dataset
uspto-grants-1980_06
Patent number
US04209611

Reaction notes

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