Magnesium orthosilicate → HCID 1478870, compound

HRID 1707053Notes

Reaction equation

HRID 1707053 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:10])[CH3:9].CO[CH:13](OC)[N:14]([CH3:16])[CH3:15].[Si]([O-])([O-])([O-])[O-].[Mg+2].[Mg+2]>C(Cl)Cl>[CH3:13][N:14]([CH3:16])[CH:15]=[CH:9][C:8]([C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[F:1])=[O:10]

Participants

5

Reactant 3

HCID 66225Magnesium orthosilicateHCID 78373Dimethylformamide dimethyl acetalHCID 96744o-Fluoroacetophenone

Product 1

HCID 1478870HCID 1478870, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A mixture of 25.0 g. of o-fluoroacetophenone and 35 ml. of dimethylformamide dimethylacetal is refluxed for 16 hours. Evaporation gives a thick oil which is dissolved in methylene chloride and passed through a short column of hydrous magnesium silicate. Evaporation of the solvent gives 34.2 g. of the desired compound as an oil.

Workup

  1. additionA mixture of 25.0 g
  2. customEvaporation
  3. customgives a thick oil which
  4. customEvaporation of the solvent
  5. customgives 34.2 g

Sources & evidence

ORD record
ord-3c095e3aabc94467adbbb5b2c391bfa5
Source dataset
uspto-grants-1980_06
Patent number
US04209621

Reaction notes

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