反应详情

Add 70 ml of water, 150 ml of glacial acetic acid and 100 g. of 3-amino-4-chloro-2-methylthiomethylbenzotrifluoride to a three-necked round bottom flask fitted with mechanical stirrer and condenser. Then add 535 g. of washed and neutralized Raney active nickel catalyst (Grace no. 28 in water). Heat to reflux (98° C.-100° C.) for 20 hours. Steam distill to obtain the title compound.

1. additionThen add 535 g
2. washof washed
3. temperatureHeat
4. temperatureto reflux (98° C.-100° C.) for 20 hours
5. distillationSteam distill