2-Aminopyrimidine → HCID 86748162, compound

HRID 1707213Notes

Reaction equation

HRID 1707213 reaction equation
[C:1]([OH:6])(=[O:5])[C@H:2]([CH3:4])[OH:3].[NH2:7][C:8]1[N:13]=[CH:12][CH:11]=[CH:10][N:9]=1>CO>[C:1]([O-:6])(=[O:5])[C@H:2]([CH3:4])[OH:3].[NH2:7][C:8]1[N:13]=[CH:12][CH:11]=[CH:10][NH+:9]=1

Participants

4

Reactant 2

HCID 79782-AminopyrimidineHCID 107689L-Lactic Acid

Product 1

HCID 86748162HCID 86748162, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

(S)-Lactic acid (3.0 g; 28 mmol) was dissolved in methanol (5 cm3) and added to a solution of 2-aminopyrimidine (2.7 g; 28 mmol) in methanol (5 cm3). The resulting white product was collected by filtration, recrystallized from water, and dried in vacuo. Found: C, 58.0%; H, 5.4%; N, 16.8%. Calculated for C12H13N3O3 : C, 58.28%; N, 5.31%; N, 17.00%. M.pt. 125°-127° C.

Workup

  1. filtrationThe resulting white product was collected by filtration
  2. customrecrystallized from water
  3. customdried in vacuo

Sources & evidence

ORD record
ord-d1cda7485d3f495bbaa9864d836828bf
Source dataset
uspto-grants-1994_10
Patent number
US05352388

Reaction notes

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