4-Hydroxybenzoic Acid → HCID 178420622, compound

HRID 1707216Notes

Reaction equation

HRID 1707216 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[OH:7][C:8]1[CH:16]=[CH:15][C:11]([C:12]([OH:14])=[O:13])=[CH:10][CH:9]=1>C(O)C>[OH:7][C:8]1[CH:16]=[CH:15][C:11]([C:12]([O-:14])=[O:13])=[CH:10][CH:9]=1.[NH2+:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 1354-Hydroxybenzoic AcidHCID 8082Piperidine

Product 1

HCID 178420622HCID 178420622, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Piperidine (0.85 g; 10 mmol) was added dropwise to a solution of 4-hydroxybenzoic acid (1.38 g; 10 mmol) in ethanol (10 cm3). The resulted in the precipitation of a white solid. The product was collected by filtration and recrystallized from water to produce translucent, colourless crystals. Found: C, 64.6%; H, 7.6%; N, 6.2%. Calculated for C12H17NO3 ; C, 64.55%; H, 7.69%; N, 6.24%. M.pt. 197°-199° C.

Workup

  1. customThe resulted in the precipitation of a white solid
  2. filtrationThe product was collected by filtration
  3. customrecrystallized from water
  4. customto produce translucent

Sources & evidence

ORD record
ord-605a697bf48f44ab9385d09b715d77a2
Source dataset
uspto-grants-1994_10
Patent number
US05352388

Reaction notes

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