2,4-Dihydroxybenzoic Acid → HCID 178420623, compound

HRID 1707218Notes

Reaction equation

HRID 1707218 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[OH:7][C:8]1[CH:16]=[C:15]([OH:17])[CH:14]=[CH:13][C:9]=1[C:10]([OH:12])=[O:11]>C(O)C>[OH:7][C:8]1[CH:16]=[C:15]([OH:17])[CH:14]=[CH:13][C:9]=1[C:10]([O-:12])=[O:11].[NH2+:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 14912,4-Dihydroxybenzoic AcidHCID 8082Piperidine

Product 1

HCID 178420623HCID 178420623, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Piperidine (0.85 g; 10 mmol) was added dropwise to a solution of 2,4-dihydroxybenzoic acid (1.54 g; 10 mmol) in ethanol (10 cm3). This mixture was then left at 5° C. overnight, which resulted in the precipitation of a white solid. The product was collected by filtration and recrystallized from water to produce needle-like crystals. Found: C, 61.3%; H, 7.3%; N, 5.9%. Calculated for C12H17NO4 ; C, 60.25%; H, 7.11%; N, 5.85%. M.pt. 210°-211° C.

Workup

  1. customwhich resulted in the precipitation of a white solid
  2. filtrationThe product was collected by filtration
  3. customrecrystallized from water
  4. customto produce needle-like crystals

Sources & evidence

ORD record
ord-4f85fc310235455c91f710948ecfd15e
Source dataset
uspto-grants-1994_10
Patent number
US05352388

Reaction notes

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