Nitrogen → HCID 70280657, compound

HRID 1707394Notes

Reaction equation

HRID 1707394 reaction equation
N#N.N#N.C1(C[C:12]2(CC3C=CC=CC=3)[CH2:21][CH2:20][CH2:19][C:18]3[N:17]=[C:16]([NH2:22])[C:15]([NH2:23])=[C:14]([NH:24][CH2:25][CH:26]([CH3:28])[CH3:27])[C:13]2=3)C=CC=CC=1.[C:36](Cl)(=O)[CH:37]([CH3:39])[CH3:38]>>[C:37]1([CH2:39][N:22]([CH2:14][C:13]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:12]=2)[C:16]2[C:15]3[N:23]=[C:36]([CH:37]([CH3:39])[CH3:38])[N:24]([CH2:25][CH:26]([CH3:27])[CH3:28])[C:14]=3[C:13]3[CH2:12][CH2:21][CH2:20][CH2:19][C:18]=3[N:17]=2)[CH:38]=[CH:27][CH:26]=[CH:25][CH:36]=1

Participants

4

Reactant 3

HCID 947NitrogenHCID 62325Isobutyryl chlorideHCID 86748174HCID 86748174, compound

Product 1

HCID 70280657HCID 70280657, compoundYield 136.7%

Procedure

Using the general method of Example 65, N2, N2 -bis(phenylmethyl)-5,6,7,8-tetrahydro-N4 -(2-methylpropyl)quinolin-2,3,4-triamine (0.86 g, 2.1 mmole) was reacted with isobutyryl chloride (0.217 mL, 2.1 mmole) to provide 0.67 g of the desired product as a yellow foam.

Sources & evidence

ORD record
ord-247b2dff375a477fabb6ffbe9f546244
Source dataset
uspto-grants-1994_10
Patent number
US05352784

Reaction notes

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