Acetic Acid → 4-Hydroxybenzaldehyde

HRID 1707811Notes

Reaction equation

HRID 1707811 reaction equation
[C:1]([OH:4])(=[O:3])[CH3:2].[CH:5]1[C:10]([OH:11])=[CH:9][CH:8]=[C:7]([CH3:12])[CH:6]=1>C(O)(C)(C)C>[OH:11][C:10]1[CH:9]=[CH:8][C:7]([CH:12]=[O:3])=[CH:6][CH:5]=1.[OH:11][C:10]1[CH:5]=[CH:6][C:2]([C:1]([OH:4])=[O:3])=[CH:8][CH:9]=1

Participants

5

Reactant 2

HCID 176Acetic AcidHCID 2879P-Cresol

Product 2

HCID 1264-HydroxybenzaldehydeHCID 1354-Hydroxybenzoic Acid

Reagents, catalysts & solvents 1

HCID 6386tert-ButanolSolvent

Procedure

The catalyst (1 g) prepared in Example 3 was reacted according to the operating procedure of Example 2, except that the acetic acid was replaced by tert. butanol and the reaction temperature was 80° C. The p-cresol conversion was 50%. 2.2 mmole of p-hydroxybenzaldehyde and 0.2 mmole of p-hydroxybenzoic acid were obtained.

Workup

  1. customwas 80° C

Sources & evidence

ORD record
ord-a4f30bdb21ec433fa93261e88deaedb7
Source dataset
uspto-grants-1994_10
Patent number
US05354919

Reaction notes

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