Tetrahydrofuran → HCID 178521226, compound

HRID 170899Notes

Reaction equation

HRID 170899 reaction equation
[Br:33][CH2:34][C:35](=[O:36])[O:37][CH2:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1.[CH3:45][CH2:46][N:47]([CH2:48][CH3:49])[CH2:50][CH3:51].[F:1][C:2]([c:3]1[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH:9]([CH2:14][c:15]3[cH:16][nH:17][c:18]4[cH:19][cH:20][cH:21][cH:22][c:23]34)[CH2:10][NH:11][CH2:12][CH2:13]2)[cH:24][c:25]([C:27]([F:28])([F:29])[F:30])[cH:26]1)([F:31])[F:32].[O:52]1[CH2:53][CH2:54][CH2:55][CH2:56]1>>[F:1][C:2]([c:3]1[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH:9]([CH2:14][c:15]3[cH:16][nH:17][c:18]4[cH:19][cH:20][cH:21][cH:22][c:23]34)[CH2:10][N:11]([CH2:34][C:35](=[O:36])[O:37][CH2:38][c:39]3[cH:40][cH:41][cH:42][cH:43][cH:44]3)[CH2:12][CH2:13]2)[cH:24][c:25]([C:27]([F:28])([F:29])[F:30])[cH:26]1)([F:31])[F:32]

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 62576Benzyl bromoacetateHCID 21978777[3,5-bis(trifluoromethyl)phenyl]-[2-(1H-indol-3-ylmethyl)piperazin-1-yl]methanone

Product 1

HCID 178521226HCID 178521226, compound

Sources & evidence

ORD record
ord-70d063233e8e4f1ca1a8e371ab1dc866
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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