Lithium Chloride → 1,1,1,2,2,3,3-Heptafluoro-4-chlorobutane

HRID 1709088Notes

Reaction equation

HRID 1709088 reaction equation
[Cl-:1].[Li+].[F:3][C:4]([F:24])([C:17]([F:23])([F:22])[C:18]([F:21])([F:20])[F:19])[CH2:5]OS(C1C=CC(C)=CC=1)(=O)=O>CN1CCCC1=O>[Cl:1][CH2:5][C:4]([F:24])([F:3])[C:17]([F:23])([F:22])[C:18]([F:21])([F:20])[F:19]

Participants

4

Reactant 2

HCID 433294Lithium ChlorideHCID 20633992,2,3,3,4,4,4-Heptafluorobutyl 4-methylbenzene-1-sulfonate

Product 1

HCID 1362181,1,1,2,2,3,3-Heptafluoro-4-chlorobutane

Reagents, catalysts & solvents 1

HCID 13387N-methyl-2-pyrrolidoneSolvent

Procedure

For example, to prepare 1,1-dichloro-2,2,3,3,4,4,4-heptafluorobutane, 2,2,3,3,4,4,4-heptafluorobutanol and p-toluenesulfonyl chloride are reacted to form 2,2,3,3,4,4,4-heptafluorobutyl-p-toluenesulfonate. Then, N-methylpyrrolidone, lithium chloride, and the 2,2,3,3,4,4,4-heptafluorobutyl-p-toluenesulfonate are reacted to form 1-chloro-2,2,3,3,4,4,4-heptafluorobutane. Finally, chlorine and the 1-chloro-2,2,3,3,4,4,4-heptafluorobutane are reacted to form the 1,1-dichloro-2,2,3,3,4,4,4-heptafluorobutane.

Sources & evidence

ORD record
ord-997433fad7724175b606552a18582063
Source dataset
uspto-grants-1990_08
Patent number
US04947881

Reaction notes

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