Benzene → HCID 23037598, compound

HRID 1709271Notes

Reaction equation

HRID 1709271 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[O:10][CH3:11])[CH:5]=O.C1C=CC=CC=1.[N+:18](C)([O-:20])=[O:19].[CH2:22](N)CCC>C(O)(=O)C>[N+:18]([C:5]([C:4]1[CH:7]=[CH:8][C:9]([O:10][CH3:11])=[C:2]([F:1])[CH:3]=1)=[CH2:22])([O-:20])=[O:19]

Participants

6

Reactant 4

HCID 241BenzeneHCID 6375NitromethaneHCID 8007ButylamineHCID 676963-Fluoro-p-anisaldehyde

Product 1

HCID 23037598HCID 23037598, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

After a mixture of 9.8 g of 3-fluoro-4-methoxybenzaldehyde, benzene, nitromethane, n-butylamine and acetic acid is refluxed, the reaction mixture is extracted with toluene. The extract is condensed, and the residue is recrystallized from a mixture of acetic acid and n-hexane. 10 g of α-nitro-3-fluoro-4-methoxystyrene are obtained.

Workup

  1. temperatureis refluxed
  2. extractionthe reaction mixture is extracted with toluene
  3. customcondensed
  4. customthe residue is recrystallized from a mixture of acetic acid and n-hexane

Sources & evidence

ORD record
ord-e951048f4547420fbb826d0bf15a7f18
Source dataset
uspto-grants-1990_08
Patent number
US04948810

Reaction notes

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