Hydrochloric Acid → HCID 13826033, compound

HRID 1709289Notes

Reaction equation

HRID 1709289 reaction equation
O[CH:2]([C:5]1[CH:23]=[CH:22][C:8]([CH2:9][CH2:10][NH:11][S:12]([C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=2)(=[O:14])=[O:13])=[CH:7][CH:6]=1)[CH2:3][CH3:4].C(Cl)[Cl:25].Cl>O>[Cl:25][CH:2]([C:5]1[CH:23]=[CH:22][C:8]([CH2:9][CH2:10][NH:11][S:12]([C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=2)(=[O:14])=[O:13])=[CH:7][CH:6]=1)[CH2:3][CH3:4]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 13826029HCID 13826029, compound

Product 1

HCID 13826033HCID 13826033, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 26.7 g. (75.4 mmole) 4-chlorobenzenesulphonic acid-4-(1-hydroxypropyl)-phenethyamide], 200 ml. methylene chloride and 100 ml. concentrated hydrochloric acid is vigorously stirred for 1 hour, then diluted with water and the methylene chloride phase is separated off. It is washed with water and sodium bicarbonate solution, dried with anhydrous sodium sulphate and evaporated. Yield quantitative; m.p. 90°-91° C.

Workup

  1. additionA mixture of 26.7 g
  2. customthe methylene chloride phase is separated off
  3. washIt is washed with water and sodium bicarbonate solution
  4. dry with materialdried with anhydrous sodium sulphate
  5. customevaporated
  6. customYield quantitative

Sources & evidence

ORD record
ord-08843369ed4c4907bf86553fc6141073
Source dataset
uspto-grants-1990_08
Patent number
US04948809

Reaction notes

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