HCID 23036562, compound → HCID 23036549, compound

HRID 1709695Notes

Reaction equation

HRID 1709695 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:12]=[CH:11][N:10]([C:13]3[C:18]([Cl:19])=[CH:17][C:16]([N+:20]([O-])=O)=[CH:15][C:14]=3[Cl:23])[N:9]=2)=[CH:4][CH:3]=1>C1COCC1.C(O)C.[Pt](=O)=O>[Cl:23][C:14]1[CH:15]=[C:16]([CH:17]=[C:18]([Cl:19])[C:13]=1[N:10]1[CH:11]=[CH:12][C:8]([C:5]2[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=2)=[N:9]1)[NH2:20]

Participants

4

Reactant 1

HCID 23036562HCID 23036562, compound

Product 1

HCID 23036549HCID 23036549, compound

Reagents, catalysts & solvents 2

HCID 345198Adams' catalystCatalystHCID 21873804Tetrahydrofuran ethanolSolvent

Procedure

A solution of 3-(4-chlorophenyl)-1-(2,6-dichloro-4-nitrophenyl)-pyrazole (0.69 g, 1.87 mmol), prepared following the procedure of Example 9, in THF/ethanol (1:4; 35 ml) is treated with platinum dioxide (43 mg) and stirred under H2 at atmospheric pressure for 2 hours. The reaction mixture is filtered and concentrated to give 3,5-dichloro-4-[3-(4-chlorophenyl)-1-pyrazolyl]aniline.

Workup

  1. filtrationThe reaction mixture is filtered
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-e5c4394dd00e448786a79bc299f1ccb5
Source dataset
uspto-grants-1990_08
Patent number
US04950678

Reaction notes

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