1,2-Dichloroethane → HCID 19819138, compound

HRID 1710257Notes

Reaction equation

HRID 1710257 reaction equation
Cl[CH2:2][CH2:3][C:4](Cl)=[O:5].[Cl-:7].[Al+3].[Cl-].[Cl-].C[C:12]1[CH:13]=[CH:14][C:15]([CH3:18])=[CH:16][CH:17]=1.Cl.[CH2:20](Cl)CCl>>[Cl:7][CH:3]([CH3:2])[C:4]([C:15]1([CH3:18])[CH:16]=[C:17]([CH3:20])[CH:12]=[CH:13][CH2:14]1)=[O:5]

Participants

6

Reactant 5

HCID 111,2-DichloroethaneHCID 313Hydrochloric AcidHCID 7809P-XyleneHCID 693643-Chloropropionyl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 19819138HCID 19819138, compound

Procedure

β-Chloropropionyl chloride (71.9 g, 566 mole) was added to a mixture of aluminium chloride (75.5 g, 566 mmole) and ethylene dichloride (200 ml). To this mixture was added p-xylene (60.0 g, 566 mmole) and the solution was stirred at room temperature for 30 minutes, then poured into dilute hydrochloric acid. The organic layer was separated, washed with water and dried over anhydrous sodium sulfate. Evaporation of the solvent under reduced pressure gave 2-(2-chloropropionyl)-2,4-dimethylbenzene a yellowish oil, which was used immediately in the next step of the sequence.

Workup

  1. customThe organic layer was separated
  2. washwashed with water
  3. dry with materialdried over anhydrous sodium sulfate
  4. customEvaporation of the solvent under reduced pressure

Sources & evidence

ORD record
ord-1acb1465fb9442d8a6b970742060a542
Source dataset
uspto-grants-1990_08
Patent number
US04952722

Reaction notes

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