1,2-Dichloroethane → 3-(5-imidazol-1-yl-6-methoxy-2-pyridinyl)-N-[2-oxo-3-[2-(trifluoromethyl)phenyl]piperidin-1-yl]prop-2-enamide
Reaction equation
[C:47](=[O:48])([OH:49])[O-:50].[CH2:57]([Cl:58])[CH2:59][Cl:60].[NH2:11][N:12]1[C:13](=[O:28])[CH:14]([c:18]2[c:19]([C:24]([F:25])([F:26])[F:27])[cH:20][cH:21][cH:22][cH:23]2)[CH2:15][CH2:16][CH2:17]1.[Na+:51].[O:52]=[CH:53][N:54]([CH3:55])[CH3:56].[OH:1][n:2]1[c:3]2[c:4]([cH:5][cH:6][cH:7][cH:8]2)[n:9][n:10]1.[n:29]1(-[c:34]2[cH:35][cH:36][c:37]([CH:42]=[CH:43][C:44](=[O:45])[OH:46])[n:38][c:39]2[O:40][CH3:41])[cH:30][n:31][cH:32][cH:33]1>>[NH:11]([N:12]1[C:13](=[O:28])[CH:14]([c:18]2[c:19]([C:24]([F:25])([F:26])[F:27])[cH:20][cH:21][cH:22][cH:23]2)[CH2:15][CH2:16][CH2:17]1)[C:44]([CH:43]=[CH:42][c:37]1[cH:36][cH:35][c:34](-[n:29]2[cH:30][n:31][cH:32][cH:33]2)[c:39]([O:40][CH3:41])[n:38]1)=[O:45]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-a3afdedc174b43f4aca50e2b9c41f216
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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