Hydrochloric Acid → 5-(2,6-difluorophenyl)-3-{[1-(ethylsulphonyl)piperidin-4-yl]amino}-1H-pyrazolo[4,3-c]isoquinoline-7-carbaldehyde oxime
Reaction equation
[ClH:38].[F:1][c:2]1[c:3](-[c:9]2[n:10][c:11]3[c:12]([c:13]4[cH:14][cH:15][c:16]([CH:19]=[O:20])[cH:17][c:18]24)[nH:21][n:22][c:23]3[NH:24][CH:25]2[CH2:26][CH2:27][N:28]([S:31](=[O:32])(=[O:33])[CH2:34][CH3:35])[CH2:29][CH2:30]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1.[NH2:36][OH:37].[cH:39]1[cH:40][cH:41][n:42][cH:43][cH:44]1>>[F:1][c:2]1[c:3](-[c:9]2[n:10][c:11]3[c:12]([c:13]4[cH:14][cH:15][c:16]([CH:19]=[N:36][OH:37])[cH:17][c:18]24)[nH:21][n:22][c:23]3[NH:24][CH:25]2[CH2:26][CH2:27][N:28]([S:31](=[O:32])(=[O:33])[CH2:34][CH3:35])[CH2:29][CH2:30]2)[c:4]([F:8])[cH:5][cH:6][cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-0f1395ee5bff4192b60d7c9a78d357f6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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