Imidazole → 3-({[tert-Butyl(diphenyl)silyl]oxy}methyl)piperidin-2-one
Reaction equation
[C:15]([CH3:16])([CH3:17])([CH3:18])[Si:19]([c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)([c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)[Cl:32].[CH3:34][N:35]([CH3:36])[CH:37]=[O:38].[OH2:33].[OH:1][CH2:2][CH:3]1[C:4](=[O:9])[NH:5][CH2:6][CH2:7][CH2:8]1.[nH:10]1[cH:11][cH:12][n:13][cH:14]1>>[O:1]([CH2:2][CH:3]1[C:4](=[O:9])[NH:5][CH2:6][CH2:7][CH2:8]1)[Si:19]([C:15]([CH3:16])([CH3:17])[CH3:18])([c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1)[c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1Participants
6
Sources & evidence
- ORD record
- ord-1b6119e8c8d14952baaaba35c67ecda8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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