Hydrochloric Acid → HCID 23642228, compound

HRID 1715052Notes

Reaction equation

HRID 1715052 reaction equation
C(O[C:6](=O)[N:7]([CH2:9][C:10]1[C:19]2[C:14](=[CH:15][C:16]([S:20]([C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)(=[O:22])=[O:21])=[CH:17][CH:18]=2)[CH:13]=[CH:12][CH:11]=1)C)(C)(C)C.Cl>C(OCC)C>[C:23]1([S:20]([C:16]2[CH:15]=[C:14]3[C:19](=[CH:18][CH:17]=2)[C:10]([CH2:9][NH:7][CH3:6])=[CH:11][CH:12]=[CH:13]3)(=[O:22])=[O:21])[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 68507399HCID 68507399, compound

Product 1

HCID 23642228HCID 23642228, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of 0.245 g (0.6 mmoles) (6-benzenesulfonyl-naphthalen-1-ylmethyl)-methyl-carbamic acid tert-butyl ester and 20 mL 2 M hydrogen chloride in ethyl ether was stirred at 23° C. for 20 hours. The resulting white solid was collected by filtration and dried in vacuo to provide (6-benzenesulfonyl-naphthalen-1-ylmethyl)-methyl-amine as a hydrochloride salt, 0.12 gram (57%), M+H=312.

Workup

  1. filtrationThe resulting white solid was collected by filtration
  2. customdried in vacuo

Sources & evidence

ORD record
ord-9499dda1bbc84c7f869c8b4b712fe9d9
Source dataset
uspto-grants-2010_09
Patent number
US07799797B2

Reaction notes

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