Water → HCID 10947700, compound

HRID 1719113Notes

Reaction equation

HRID 1719113 reaction equation
[S-2].[Na+].[Na+].S(C1C=CC(C)=CC=1)([O-])(=O)=O.[Cl:15][C:16]1[CH:37]=[CH:36][C:19]([O:20][CH:21]([O:28][C:29]2[CH:34]=[CH:33][C:32]([Cl:35])=[CH:31][CH:30]=2)[CH:22](O)[C:23]([CH3:26])([CH3:25])[CH3:24])=[CH:18][CH:17]=1.O>CS(C)=O>[Cl:15][C:16]1[CH:17]=[CH:18][C:19]([O:20][C:21]([O:28][C:29]2[CH:30]=[CH:31][C:32]([Cl:35])=[CH:33][CH:34]=2)=[CH:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[CH:36][CH:37]=1

Participants

6

Reactant 4

HCID 962WaterHCID 14804Sodium SulfideHCID 85570p-ToluenesulfonateHCID 14000234HCID 14000234, compound

Product 1

HCID 10947700HCID 10947700, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Conditions

Temperature
120 °C

Procedure

39 g (0.5 mole) of sodium sulfide were added to 47.8 g (0.1 mole) of the tosylate of 1,1-bis-(4-chlorophenoxy)-3,3-dimethylbutan-2-ol in 200 ml of dry dimethyl sulfoxide, and the mixture was stirred at 120° C. until the starting compound was no longer detectable by high-pressure liquid chromatography (HPLC). Thereafter, the mixture was cooled, water was added, the mixture was extracted twice with the same volume of ethyl acetate, the extracts were dried and the solvent was distilled off under reduced pressure.

Workup

  1. temperatureThereafter, the mixture was cooled
  2. extractionthe mixture was extracted twice with the same volume of ethyl acetate
  3. customthe extracts were dried
  4. distillationthe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-d1e090bbd8d94424a7abafbd3d2d1a13
Source dataset
uspto-grants-1985_09
Patent number
US04539160

Reaction notes

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