Hydrochloric Acid → HCID 13533194, compound

HRID 1719132Notes

Reaction equation

HRID 1719132 reaction equation
C([O:5][C:6]([CH2:8][N:9]1[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=2[S:13][CH:12]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:11]([NH:26][CH2:27][C:28]([O:30][CH2:31][CH3:32])=[O:29])[C:10]1=[O:33])=[O:7])(C)(C)C.CCOCC.[ClH:39]>O1CCOCC1>[ClH:39].[C:6]([CH2:8][N:9]1[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=2[S:13][CH:12]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:11]([NH:26][CH2:27][C:28]([O:30][CH2:31][CH3:32])=[O:29])[C:10]1=[O:33])([OH:7])=[O:5]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 20267561HCID 20267561, compound

Product 1

HCID 13533194HCID 13533194, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

1.2 g of the compound obtained in Example 24 was dissolved in 10 ml of a 6N solution of hydrogen chloride in dioxane, and the resulting solution was stirred at room temperature for 2 hours. Then, ether was added thereto so as to cause crystallization. The precipitated crystals were separated by filtration and washed with ether to obtain 1.0 g of the desired compound.

Workup

  1. customcrystallization
  2. customThe precipitated crystals were separated by filtration
  3. washwashed with ether

Sources & evidence

ORD record
ord-80d898f6afdb46ef881ed22ba9f26c76
Source dataset
uspto-grants-1985_09
Patent number
US04539150

Reaction notes

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