Water → HCID 10041022, compound

HRID 1719255Notes

Reaction equation

HRID 1719255 reaction equation
[N+]([O-])(O)=O.[Cl:5]/[C:6](/[C:13]1[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=1[Cl:20])=[CH:7]/[N:8]1[CH:12]=[CH:11][N:10]=[CH:9]1.O.C(=O)([O-])[O-].[K+].[K+]>ClC(Cl)Cl>[ClH:5].[Cl:5]/[C:6](/[C:13]1[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=1[Cl:20])=[CH:7]/[N:8]1[CH:12]=[CH:11][N:10]=[CH:9]1

Participants

5

Reactant 3

HCID 962WaterHCID 11430Potassium CarbonateHCID 86740283HCID 86740283, compound

Product 1

HCID 10041022HCID 10041022, compoundYield 86%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

To a stirred mixture of 1.9 parts of (E)-1-[2-chloro-2-(2,4-dichlorophenyl)ethenyl]-1H-imidazole mononitrate in a mixture of 50 parts of water and 75 parts of trichloromethane was added 1.0 part of potassium carbonate. The whole was stirred till a clear solution was obtained (pH 8-9). The organic layer was separated, dried, filtered and evaporated. The residue was converted into the hydrochloride salt in 4-methyl-2-pentanone, 2,2'-oxybispropane and 2-propanol. The salt was filtered off and dried, yielding 1.5 parts (86%) of (E)-1-[2-chloro-2-(2,4-dichlorophenyl)ethenyl]-1H-imidazole monohydrochloride; mp. 203.2° C. (compound 24).

Workup

  1. customwas obtained (pH 8-9)
  2. customThe organic layer was separated
  3. customdried
  4. filtrationfiltered
  5. customevaporated
  6. filtrationThe salt was filtered off
  7. customdried

Sources & evidence

ORD record
ord-090167357a3f46988840a870ebc1c3e7
Source dataset
uspto-grants-1985_09
Patent number
US04539325

Reaction notes

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