Dimethylformamide → HCID 70475162, compound

HRID 1719566Notes

Reaction equation

HRID 1719566 reaction equation
ClC[C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]=1[CH3:13].[C-:14]#N.[Na+].[CH3:17][N:18](C)C=O>O>[CH3:14][C:4]1([CH2:13][C:17]#[N:18])[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[CH:11]=[CH:12][CH2:3]1

Participants

5

Reactant 3

HCID 6228DimethylformamideHCID 8929Sodium CyanideHCID 199951842-(Chloromethyl)-1-methylnaphthalene

Product 1

HCID 70475162HCID 70475162, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 6.0 g of 2-chloromethyl-1-methylnaphthalene, 3.0 g of sodium cyanide and 75 ml of dimethylformamide was stirred for two hours at room temperature. Water (150 ml) was then added and stirring continued for one hour longer. The solid which had separated was collected by filtration and dried to give 5.0 g of 1-methylnaphthaleneacetonitrile as a pale tan solid.

Workup

  1. stirringstirring
  2. waitcontinued for one hour
  3. customThe solid which had separated
  4. filtrationwas collected by filtration
  5. customdried

Sources & evidence

ORD record
ord-c35e6ac8fab04b8bb727ac61ee55cbeb
Source dataset
uspto-grants-1985_09
Patent number
US04540705

Reaction notes

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