Dimethylformamide → 5-[1-[2-[4-Chloro-8-oxo-9-(2,2,2-trifluoroethyl)-3,6,7,10-tetrahydropyrazolo[3,4-i][2]benzazepin-7-yl]acetyl]piperidin-4-yl]imidazolidine-2,4-dione
Reaction equation
[B-:39]([F:40])([F:41])([F:42])[F:43].[CH3:61][CH2:62][N:63]([CH2:64][CH3:65])[CH2:66][CH3:67].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([c:6]3[cH:7][n:8][nH:9][c:10]13)[CH2:11][N:12]([CH2:21][C:22]([F:23])([F:24])[F:25])[C:13](=[O:20])[CH:14]([CH2:16][C:17](=[O:18])[OH:19])[CH2:15]2.[NH:26]1[CH2:27][CH2:28][CH:29]([CH:32]2[C:33](=[O:38])[NH:34][C:35](=[O:37])[NH:36]2)[CH2:30][CH2:31]1.[O:68]=[CH:69][N:70]([CH3:71])[CH3:72].[n:44]1([O:45][C:46]([N:47]([CH3:48])[CH3:49])=[N+:50]([CH3:51])[CH3:52])[c:53]2[cH:54][cH:55][cH:56][cH:57][c:58]2[n:59][n:60]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([c:6]3[cH:7][n:8][nH:9][c:10]13)[CH2:11][N:12]([CH2:21][C:22]([F:23])([F:24])[F:25])[C:13](=[O:20])[CH:14]([CH2:16][C:17](=[O:18])[N:26]1[CH2:27][CH2:28][CH:29]([CH:32]3[C:33](=[O:38])[NH:34][C:35](=[O:37])[NH:36]3)[CH2:30][CH2:31]1)[CH2:15]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-21032d35e7f24631a1d99100c8525d7e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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