Sodium Sulfite → HCID 86749374, compound

HRID 1720030Notes

Reaction equation

HRID 1720030 reaction equation
[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6]Br)=[C:4]([N+:10]([O-:12])=[O:11])[CH:3]=1.[S:13]([O-:16])([O-:15])=[O:14].[Na+:17].[Na+]>O>[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][S:13]([O-:16])(=[O:15])=[O:14])=[C:4]([N+:10]([O-:12])=[O:11])[CH:3]=1.[Na+:17]

Participants

4

Reactant 2

HCID 24437Sodium SulfiteHCID 127613791-(Bromomethyl)-4-fluoro-2-nitrobenzene

Product 1

HCID 86749374HCID 86749374, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 4-fluoro-2-nitrobenzylbromide (50.1 g) and sodium sulfite (27.3 g) in water (200 ml) was heated under reflux for 2.5 hours and cooled to room temperature. The solvent was removed under reduced pressure and ethanol (100 ml) was added to the crude product.

Workup

  1. temperatureunder reflux for 2.5 hours
  2. customThe solvent was removed under reduced pressure and ethanol (100 ml)
  3. additionwas added to the crude product

Sources & evidence

ORD record
ord-d2b5e084fb4946508147eb1d65cfcb51
Source dataset
uspto-grants-1996_04
Patent number
US05504095

Reaction notes

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