HRID1720811

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6422

未命名化合物

结构：CCCCCCCCCCCCCCCC(=O)OCC(CSCCC(=O)NCC(=O)NCC(=O)NCC(=O)OC(C)(C)C)OC(=O)CCCCCCCCCCCCCCC

HCID22418631

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCC(=O)OCC(CSCCC(=O)NCC(=O)NCC(=O)NCC(=O)O)OC(=O)CCCCCCCCCCCCCCC

HCID22418620

未命名化合物

收率 86%

PROCEDURE

实验过程

(6,7-bis(palmitoyloxy)-4-thiaheptanoyl)glycylglycylglycine t-butyl ester as obtained in Example 5 (110 mg) was mixed with trifiuoroacetic acid (5 ml), followed by stirring at room temperature for 1 hour. The mixture was concentrated to yield the title compound (81 mg, yield 86%) as a colorless crystal.

WORKUP

后处理

concentrationThe mixture was concentrated

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-96b46bfa02ea424c9898eec59b97bcac
来源数据集: uspto-grants-1996_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05506267
来源说明: uspto-grants-1996_04

反应 SMILES

C([O:5][C:6](=[O:61])[CH2:7][NH:8][C:9](=[O:60])[CH2:10][NH:11][C:12](=[O:59])[CH2:13][NH:14][C:15](=[O:58])[CH2:16][CH2:17][S:18][CH2:19][CH:20]([O:40][C:41](=[O:57])[CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH3:56])[CH2:21][O:22][C:23](=[O:39])[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])(C)(C)C.FC(F)(F)C(O)=O>>[C:41]([O:40][CH:20]([CH2:21][O:22][C:23](=[O:39])[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[CH2:19][S:18][CH2:17][CH2:16][C:15]([NH:14][CH2:13][C:12]([NH:11][CH2:10][C:9]([NH:8][CH2:7][C:6]([OH:61])=[O:5])=[O:60])=[O:59])=[O:58])(=[O:57])[CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH3:56]