Triethylamine → HCID 14054697, compound

HRID 1722722Notes

Reaction equation

HRID 1722722 reaction equation
F[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9].[F:11][C:12]1[CH:13]=[C:14]([CH:17]=[C:18]([F:20])[CH:19]=1)[CH2:15][NH2:16].C(N(CC)CC)C>>[F:11][C:12]1[CH:13]=[C:14]([CH:17]=[C:18]([F:20])[CH:19]=1)[CH2:15][NH:16][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9]

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 738951-Fluoro-2-nitrobenzeneHCID 1452113,5-Difluorobenzylamine

Product 1

HCID 14054697HCID 14054697, compoundYield 100.9%

Procedure

Reaction of 2-fluoronitrobenzene (3 g, 21 mmole), 3,5-difluorobenzylamine, (3 g, 21 mmole) and triethylamine (2.6 g, 26.2 mmole) substantially as described in 1C above produced 5.6 g (100%) of title compound as orange crystals: mp 104°-105°.

Sources & evidence

ORD record
ord-b4471335d24747e78a4b4a8098e1fce4
Source dataset
uspto-grants-1989_08
Patent number
US04857540

Reaction notes

Loading…