Methyl Bromide → HCID 11244270, compound

HRID 1723474Notes

Reaction equation

HRID 1723474 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][N:11]=[CH:10][C:9]=2[C:14]([O:16][CH3:17])=[O:15])=[CH:4][CH:3]=1.[CH3:18][Br:19]>CC(C)=O>[Br-:19].[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][N+:11]([CH3:18])=[CH:10][C:9]=2[C:14]([O:16][CH3:17])=[O:15])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 6323Methyl BromideHCID 11806499HCID 11806499, compound

Product 1

HCID 11244270HCID 11244270, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

The crude pyridine (5.95 g) was treated with methyl bromide (2.2 ml) in acetone (25 ml). After heating in a sealed vessel at 53° for 60 hours and cooling to 0°, the title pyridinium salt was collected by filtration, washed with acetone and dried (7.4 g, 88%), m.p. 165°-170° (decomp.).

Workup

  1. temperatureAfter heating in a sealed vessel at 53° for 60 hours
  2. temperaturecooling to 0°
  3. filtrationthe title pyridinium salt was collected by filtration
  4. washwashed with acetone
  5. customdried (7.4 g, 88%), m.p. 165°-170° (decomp.)

Sources & evidence

ORD record
ord-29d7221a4db641b2bbc615bd7ea99063
Source dataset
uspto-grants-1989_08
Patent number
US04861893

Reaction notes

Loading…