Hydrochloric Acid → HCID 10134275, compound

HRID 1723507Notes

Reaction equation

HRID 1723507 reaction equation
Cl[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9](/[CH:12]=[CH:13]/[C:14]2[O:15][C:16]3[CH:22]=[CH:21][CH:20]=[CH:19][C:17]=3[N:18]=2)=[CH:8][CH:7]=1.[CH2:23]([NH:26][CH2:27][CH2:28][CH3:29])[CH2:24][CH3:25].Cl>>[CH2:23]([N:26]([CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9](/[CH:12]=[CH:13]/[C:14]2[O:15][C:16]3[CH:22]=[CH:21][CH:20]=[CH:19][C:17]=3[N:18]=2)=[CH:8][CH:7]=1)[CH2:27][CH2:28][CH3:29])[CH2:24][CH3:25]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8902DipropylamineHCID 14146343HCID 14146343, compound

Product 1

HCID 10134275HCID 10134275, compoundYield 40%

Procedure

The title compound was prepared as described in Example 8 starting with (C) of Example 8 (2.0 g, 6.4 mmol) and using dipropylamine in place of dibutylamine to produce 1.2 g (40% yield) of the title compound as the HCl salt, mp 172°-173° C. IR(KBr): 3400, 1600 cm-1. MS: 379(MH+). 1H NMR (CDCl3): δ 8.48-6.95 (m, 10H), 4.19 (t, J=5.1 Hz, 2H), 3.21 (m, 6H), 2.49-0.91 (m, 12H).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-8a5008c6d76f4ba396bb9c18d3785e78
Source dataset
uspto-grants-1989_08
Patent number
US04861897

Reaction notes

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