Hydrochloric Acid → HCID 18435659, compound

HRID 1723513Notes

Reaction equation

HRID 1723513 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1/[CH:13]=[CH:14]/[C:15]1[O:16][C:17]2[CH:23]=[CH:22][CH:21]=[CH:20][C:18]=2[N:19]=1.[NH:24]1[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1.Cl>>[N:24]1([CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2/[CH:13]=[CH:14]/[C:15]2[O:16][C:17]3[CH:23]=[CH:22][CH:21]=[CH:20][C:18]=3[N:19]=2)[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8082PiperidineHCID 18435640HCID 18435640, compound

Product 1

HCID 18435659HCID 18435659, compoundYield 42%

Procedure

The title compound was prepared as described in Example 18 starting with (D) of Example 18 (2.5 g, 7.6 mmmol) and using piperidine in place of dibutylamine to produce 1.2 g (42% yield) of the title compound as the HCl salt, mp 230°-232° C. IR(KBr): 1600 cm-1. MS: 377(MH+). 1H NMR (DMSO): δ 7.91-6.95 (m, 10H), 3.99 (t, J=5.2 Hz, 2H), 3.10 (m, 6H), 1.75 (m, 10H).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-97f10f79ecfb4b61aa7ec9dab23f850a
Source dataset
uspto-grants-1989_08
Patent number
US04861897

Reaction notes

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