Hydrochloric Acid → HCID 18435647, compound

HRID 1723514Notes

Reaction equation

HRID 1723514 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1/[CH:13]=[CH:14]/[C:15]1[O:16][C:17]2[CH:23]=[CH:22][CH:21]=[CH:20][C:18]=2[N:19]=1.[CH2:24]([NH:27][CH2:28][CH2:29][CH3:30])[CH2:25][CH3:26].Cl>>[CH2:24]([N:27]([CH2:28][CH2:29][CH3:30])[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1/[CH:13]=[CH:14]/[C:15]1[O:16][C:17]2[CH:23]=[CH:22][CH:21]=[CH:20][C:18]=2[N:19]=1)[CH2:25][CH3:26]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8902DipropylamineHCID 18435640HCID 18435640, compound

Product 1

HCID 18435647HCID 18435647, compoundYield 30%

Procedure

The procedure of Example 18 was followed starting with (D) of Example 18 (2.5 g, 7.6 mmol) and using dipropylamine in place of dibutylamine to produce 0.90 g (30% yield) of the named compound as the HCl salt, mp 150°-152° C. IR(KBR): 1600 cm-1. MS: 393(MH+). 1H NMR (CDCl3): δ 8.09-6.87 (m, 10H), 4.01 (t, J=5.4 Hz, 2H), 3.02 (m, 6H), 1.95 (m, 8H), 0.99 (m, 6H).

Sources & evidence

ORD record
ord-2ce1dd42433d4964b73bb2e8ed6ae2d6
Source dataset
uspto-grants-1989_08
Patent number
US04861897

Reaction notes

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