Tetrahydrofuran → 3-(Aminomethyl)-1-benzylpiperidin-4-ol
Reaction equation
[Al+3:18].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([C:15]#[N:16])[CH:11]([OH:14])[CH2:12][CH2:13]1.[H-:17].[H-:20].[H-:21].[H-:22].[Li+:19].[O:23]1[CH2:24][CH2:25][CH2:26][CH2:27]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([CH2:15][NH2:16])[CH:11]([OH:14])[CH2:12][CH2:13]1Participants
6
Sources & evidence
- ORD record
- ord-ab451e66a178443da9ac1fef59579c1f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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