Hydrazine hydrate (1:1) → HCID 86023618, compound

HRID 1724713Notes

Reaction equation

HRID 1724713 reaction equation
O.NN.O=C1C2C(=CC=CC=2)C(=O)[N:6]1[CH2:15][C:16]([P:19](=[O:26])([O:23][CH2:24][CH3:25])[O:20][CH2:21][CH3:22])([F:18])[F:17]>C(Cl)Cl>[NH2:6][CH2:15][C:16]([P:19](=[O:26])([O:23][CH2:24][CH3:25])[O:20][CH2:21][CH3:22])([F:17])[F:18]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 86606190HCID 86606190, compound

Product 1

HCID 86023618HCID 86023618, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Hydrazine monohydrate was added to a methylene chloride solution of diethyl [2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1,1-difluoroethyl]phosphonate, for stirring at ambient temperature for one hour, to obtain diethyl (2-amino-1,1-difluoroethyl)phosphonate.

Sources & evidence

ORD record
ord-efdd873ef6424f818e22ca9528e71845
Source dataset
uspto-grants-2009_02
Patent number
US07488739B2

Reaction notes

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