反应详情

温度

50 °C

A suspension of 939 mg of 1-(5-benzyloxyindazol-1-yl)ethanone, 1.33 g of ammonium formate and 939 mg of palladium-on-charcoal at 10% in 100 ml of absolute ethanol is heated at around 50° C. for about thirty minutes. When gas is no longer being given off, the catalyst is filtered through a paper filter and rinsed with absolute ethanol. The filtrate is concentrated under reduced pressure in a rotary evaporator to obtain 571.1 mg of 1-(5-hydroxyindazol-1-yl)ethanone.

1. filtrationthe catalyst is filtered through a paper
2. filtrationfilter
3. washrinsed with absolute ethanol
4. concentrationThe filtrate is concentrated under reduced pressure in a rotary evaporator