Tributylstannane → HCID 18177020, compound

HRID 1726111Notes

Reaction equation

HRID 1726111 reaction equation
CC(N=NC(C#N)(C)C)(C#N)C.C([SnH](CCCC)CCCC)CCC.[C:26]1([CH3:61])[C:27]([S:32]([N:35]2[CH2:45][C:44]3=[CH:46][CH:36]2[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH:43]3[CH:47](OC(=S)OC2C=CC=CC=2)[CH2:48][CH2:49][CH3:50])(=[O:34])=[O:33])=[CH:28][CH:29]=[CH:30][CH:31]=1>C1(C)C=CC=CC=1>[CH2:47]([CH:43]1[CH2:42][CH2:41][CH2:40][CH2:39][CH2:38][CH2:37][CH:36]2[CH:46]=[C:44]1[CH2:45][N:35]2[S:32]([C:27]1[C:26]([CH3:61])=[CH:31][CH:30]=[CH:29][CH:28]=1)(=[O:33])=[O:34])[CH2:48][CH2:49][CH3:50]

Participants

5

Reactant 3

HCID 5948TributylstannaneHCID 6547AzobisisobutyronitrileHCID 86587139HCID 86587139, compound

Product 1

HCID 18177020HCID 18177020, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Conditions

Temperature
75 °C

Procedure

AIBN (0.20 mmol) and tri-n-butyltinhydride (2.0 mmol) are added to a solution of the product of Example 7 (1 mmol) in toluene (10 mL). The mixture is stirred at 75° C. until reaction is complete as detected by thin-layer chromatography. Solvent is removed under reduced pressure and the residue is purified using high-performance liquid chromatography, affording the above-titled compound.

Workup

  1. customSolvent is removed under reduced pressure
  2. customthe residue is purified

Sources & evidence

ORD record
ord-b568ca7897cf4daebc2ddd5400357b99
Source dataset
uspto-grants-2009_02
Patent number
US07491745B2

Reaction notes

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