Triphenylphosphine → HCID 86595689, compound

HRID 1726532Notes

Reaction equation

HRID 1726532 reaction equation
O[C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][C:8](=[O:12])[O:9]2)=[CH:4][CH:3]=1.[Cl:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]O.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C(OC(N=NC(OCC)=O)=O)C>C1(C)C=CC=CC=1>[Cl:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][C:8](=[O:12])[O:9]2)=[CH:4][CH:3]=1

Participants

6

Reactant 4

HCID 11776TriphenylphosphineHCID 748286-Chloro-1-hexanolHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 5281426Umbelliferone

Product 1

HCID 86595689HCID 86595689, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Preparation can be carried out analogously to Synthetic Example 1 using 16.2 g (100 mmol) 7-Hydroxycoumarin, 14.3 g (105 mmol) 6-chlorohexanol, 28.8 g (110 mmol) triphenylphosphine and 47.9 g (110 mmol) of a 40% solution of azodicarboxylic acid diethyl ester in toluene to yielded 7-(6-chlorohexyl) coumarin.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-43cb210687cc421287200db87b4e9930
Source dataset
uspto-grants-2009_02
Patent number
US07491752B2

Reaction notes

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