Triphenylphosphine → HCID 86595690, compound

HRID 1726533Notes

Reaction equation

HRID 1726533 reaction equation
[O:1]=[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][C:6]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][O:19][C:20](=[O:49])[C:21]3[CH:47]=[C:46]([OH:48])[CH:45]=[C:23]([C:24]([O:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][O:33][C:34]4[CH:43]=[C:42]5[C:37]([CH:38]=[CH:39][C:40](=[O:44])[O:41]5)=[CH:36][CH:35]=4)=[O:25])[CH:22]=3)=[CH:7][CH:8]=2)[O:3]1.[Cl:50][CH2:51][CH2:52][CH2:53][CH2:54]O.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C(OC(N=NC(OCC)=O)=O)C>C1(C)C=CC=CC=1>[O:1]=[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][C:6]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][O:19][C:20](=[O:49])[C:21]3[CH:47]=[C:46]([O:48][CH2:54][CH2:53][CH2:52][CH2:51][Cl:50])[CH:45]=[C:23]([C:24]([O:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][O:33][C:34]4[CH:43]=[C:42]5[C:37]([CH:38]=[CH:39][C:40](=[O:44])[O:41]5)=[CH:36][CH:35]=4)=[O:25])[CH:22]=3)=[CH:7][CH:8]=2)[O:3]1

Participants

6

Reactant 4

HCID 11776TriphenylphosphineHCID 135694-Chloro-1-butanolHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 86595691HCID 86595691, compound

Product 1

HCID 86595690HCID 86595690, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Preparation can be carried out analogously to Synthetic Example 1 using 6.71 g (10.0 mmol) bis{6-[(2-oxo-2H-chromen-7-yl)oxy]hexyl}5-hydroxyisophthalate, 1.14 g (10.5 mmol) 4-chloro-1-butanol, 2.88 g (11.0 mmol) triphenylphosphine and 4.79 g (11.0 mmol) of a 40% solution of azodicarboxylic acid diethyl ester in toluene to yield bis{6-[(2-oxo-2H-chromen-7-yl)oxy]hexyl}5-(4-chlorobutoxy)isophthalate.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-3a5b27deb83e4005ac687e4ec16865b9
Source dataset
uspto-grants-2009_02
Patent number
US07491752B2

Reaction notes

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