HRID1726703

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID787

Hydroxylamine

H3NO

HCID887

Methanol

CH4O

结构：COC(=O)[C@H]1C[C@H](OCc2cccnc2)CC[C@@H]1C(=O)N1CCN(c2ccccc2)CC1

HCID67305585

未命名化合物

PRODUCTS

生成物

结构：O=C(NO)[C@H]1C[C@H](OCc2cccnc2)CC[C@@H]1C(=O)N1CCN(c2ccccc2)CC1

HCID86598268

未命名化合物

PROCEDURE

实验过程

1.5 M of hydroxyamine solution (0.7 ml) was added to a solution of methyl(1S,2S,5R)-2-[(4-phenylpiperazin-1-yl)carbonyl]-5-(pyridin-3-ylmethoxy)cyclohexanecarboxylate (0.075 mmol, 0.000075 mol) made above in methanol (0.5 mL, 0.01 mol). It was stirred at rt for 2 hrs then purified by Prep-HPLC. LCMS: (M+H)+=439.3.

WORKUP

后处理

customthen purified by Prep-HPLC