反应详情

TFA (4 mL) was added to a solution of compound 6 (0.93 g, 1.7 mmol) in CH2Cl2 (20 mL) and the resulting solution was stirred overnight at ambient temperature. The resulting solution was concentrated in vacuo and the residue was loaded onto a silica gel gravity column (50 g) and eluted with CH2Cl2:MeOH:NH4OH (30% aqueous) 90:10:1 (v/v) to afford compound 7 as a thick colorless oil (0.83 g, 99%).

1. concentrationThe resulting solution was concentrated in vacuo
2. washeluted with CH2Cl2